250 LOAD, 30 EOAD
Diagnosis of probable Alzheimer's disease
MRI/CT report included
All Caucasian
MMSE< 23
Subjects followed for 1 year with repeat MMSE and ADAS-cog and sampling
at 1 yr.
Clinical
data:
| MRI/CT
report |
Demographics |
Ethnicity
to grandparents |
MMSE baseline
and 1 yr |
Family history
of Alzheimer's |
Nicotine use |
ADAS-cog baseline
and 1 yr |
Diagnostic information |
Current medications |
| Psychotic symptoms |
Height weight |
Age at diagnosis |
Controls for the LOAD group are currently
being collected (MMSE > 28, no family history of Alzheimer's
disease).
Controls for the EOAD group are available from our neuropsychiatric
controls.
Gel
for 31 Alzheimers subjects

In
this picture the 1st, 20th lanes in
the top tier
and 1st and 16th lanes in the bottom tier of the gel
are
molecular weight markers (Lambda
DNA restricted
with
Hind III). The
15th lane in the bottom tier of the
gel
is our parallel processed control sample
for the set.