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Probable Alzheimer's Disease (early and late onset)
Prospective 1 Year Follow-Up


Complete:

Enrollment complete, 1 year follow-up ongoing

>50% subjects apo-E4 positive

# banked subjects

Gel for 31 Alzheimer's subjects

Inclusion:

  • 250 LOAD, 30 EOAD
  • Diagnosis of probable Alzheimer's disease
  • MRI/CT report included
  • All Caucasian
  • MMSE< 23
  • Subjects followed for 1 year with repeat MMSE and ADAS-cog and sampling at 1 yr.

Clinical data:

MRI/CT report Demographics Ethnicity to grandparents
MMSE baseline
and 1 yr
Family history of Alzheimer's Nicotine use
ADAS-cog baseline
and 1 yr
Diagnostic information Current medications
Psychotic symptoms Height weight Age at diagnosis

Controls for the LOAD group are currently being collected (MMSE > 28, no family  history of Alzheimer's disease).

Controls for the EOAD group are available from our neuropsychiatric controls.

Gel for 31 Alzheimer’s subjects

In this picture the 1st, 20th lanes in the top tier

and 1st and 16th lanes in the bottom tier of the gel

are molecular weight markers (Lambda DNA restricted

with Hind III). The 15th lane in the bottom tier of the

gel is our parallel processed control sample for the set. 

 





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