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Biofluid Samples for Oncology Research

All biofluid samples collected under our ongoing liquid biopsy protocol are available immediately and include detailed clinical data. Clinical data are collected over the course of the disease for up to five years. There may also be intermittent collection of blood and urine samples over the five-year period. Cancer types range from appendix, breast, cervical, colon, lung, prostate, stomach, and more. Matched resected tissue from solid tumors (usually pretreatment) is available. View the complete list below.

Paired plasma and resected tissue from solid tumors

Biofluid samples and their included clinical information are de-identified. PrecisionMed’s biomaterials are collected under US IRB approved protocols.

This multicenter clinical protocol is designed to collect blood, urine and tumor tissue, as well as clinical data from prospectively consented donors with known solid malignant tumors.

Recently, our understanding of the genetic basis of human disease has seen the greatest advances in the area of cancer genetics. A number of familial cancer genes with high-penetrance mutations have been identified, but the situation is far more complex since the contribution of low-penetrance genetic variants is poorly understood. A deeper understanding of the molecular pathogenesis of cancer will require further study of tissue biology and treatment response as well as new statistical and computational approaches for analysis of the genetic and signaling networks that orchestrate individual cancer susceptibility and tumor behavior. For this approach, well-annotated cancer tissue is required with liquid biopsy samples being ideal.

Cell-free DNA (cfDNA) has been shown to be elevated in the plasma of patients with malignancy. This may present an opportunity for earlier diagnosis and characterization of malignancy based on a blood draw.

Liquid Biopsy Inventory

 

Diagnosis
# Of Donors
Ampullary Cancer
  3
Anal
  3
Appendix
  1
Bladder
  51
Bladder/Prostate
  1
Breast
  137
Breast - Benign Fibromyositis
  1
Cervical
  8
Cholangiocarcinoma
  1
Colon
  8
Colorectal
  26
Endocervical
  1
Endometrial
   5
Esophageal
   4
Fallopian Tube
   1
Gastric
   2
Gastroesophageal
   1
Leiomyosarcoma
   2
Liposarcoma
   1
Liver
   2
Lung
   73
Melanoma
   2
Mouth
   1
Neoplasm of cecum
   1
Ovarian
   6
Pancreas
   12
Peritoneal Carcinomatosis
   2
Prostate
   365
Rectal
   3
Renal
   51
Renal Pelvis
   1
Salivary Gland Cancer
   1
Sarcoma
   1
Spindle cell
   1
Stomach
   1
Supraglottis
   1
Testicular
   4
Thyroid
   3
Uterine
   9
Vaginal SCC
   2

 

Request Inventory

PrecisionMed has been providing researchers with the highest quality human biological material for research since 1996. View our inventory oncology sample collections, including diseased and TruNormal® solid tissue, liquid biopsy samples, and additional banked material matched to FFPE tissue. All our samples are collected under IRB approved clinical protocols.

Our comprehensive sample collections are designed, managed and sponsored by PrecisionMed. If we don’t have it, we’ll collect it.